Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

PRODUCT NAME

KODAK REVERSAL BATH, PROCESS E-6

NFPA

PRODUCT USE

Solution used in the photographic development process.

SYNONYMS

"KAN 355080", "PCD 3993", N-0019.000, N-0019.000

Section 2 - HAZARDS IDENTIFICATION

CANADIAN WHMIS SYMBOLS

EMERGENCY OVERVIEW

RISK

Causes burns.
Risk of serious damage to eyes.

POTENTIAL HEALTH EFFECTS

ACUTE HEALTH EFFECTS

SWALLOWED

  The material can produce chemical burns within the oral cavity and gastrointestinal tract following ingestion.  The material has NOT been classified as "harmful by ingestion". This is because of the lack of corroborating animal or human evidence. The material may still be damaging to the health of the individual, following ingestion, especially where pre-existing organ (e.g. liver, kidney) damage is evident. Present definitions of harmful or toxic substances are generally based on doses producing mortality (death) rather than those producing morbidity (disease, ill-health). Gastrointestinal tract discomfort may produce nausea and vomiting. In an occupational setting however, unintentional ingestion is not thought to be cause for concern.  

EYE

  The material can produce chemical burns to the eye following direct contact. Vapors or mists may be extremely irritating.  If applied to the eyes, this material causes severe eye damage.  The material may produce severe irritation to the eye causing pronounced inflammation. Repeated or prolonged exposure to irritants may produce conjunctivitis.  Solutions of low-molecular weight organic acids cause pain and injuryto the eyes.  

SKIN

  The material can produce chemical burns following direct contactwith the skin.  Skin contact is not thought to have harmful health effects, however the material may still produce health damage following entry through wounds, lesions or abrasions.  Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may produce systemic injury with harmful effects. Examine the skin prior to the use of the material and ensure that any external damage is suitably protected.  The material may cause severe skin irritation after prolonged or repeated exposure and may produce on contact skin redness, swelling, the production of vesicles, scaling and thickening of the skin. Repeated exposures may produce severe ulceration.  

INHALED

  Not normally a hazard due to non-volatile nature of product.  The material can cause respiratory irritation in some persons. The body's response to such irritation can cause further lung damage.  The material has NOT been classified as "harmful by inhalation". This is because of the lack of corroborating animal or human evidence. In the absence of such evidence, care should nevertheless be taken to ensure exposure is kept to a minimum and that suitable control measures be used, in an occupational setting to control vapors, fumes and aerosols.  

CHRONIC HEALTH EFFECTS

  Limited evidence suggests that repeated or long-term occupational exposure may produce cumulative health effects involving organs or biochemical systems.  Asthma-like symptoms may continue for months or even years after exposure to the material ceases. This may be due to a non-allergenic condition known as reactive airways dysfunction syndrome (RADS) which can occur following exposure to high levels of highly irritating compound. Key criteria for the diagnosis of RADS include the absence of preceding respiratory disease, in a non-atopic individual, with abrupt onset of persistent asthma-like symptoms within minutes to hours of a documented exposure to the irritant. A reversible airflow pattern, on spirometry, with the presence of moderate to severe bronchial hyperreactivity on methacholine challenge testing and the lack of minimal lymphocytic inflammation, without eosinophilia, have also been included in the criteria for diagnosis of RADS. RADS (or asthma) following an irritating inhalation is an infrequent disorder with rates related to the concentration of and duration of exposure to the irritating substance. Industrial bronchitis, on the other hand, is a disorder that occurs as result of exposure due to high concentrations of irritating substance (often particulate in nature) and is completely reversible after exposure ceases. The disorder is characterised by dyspnea, cough and mucus production.  Long term exposure to organophosphonate chelating agents may cause adverse effects.  Rats fed on aminotri(methylenephosphonic acid) (ATMP), for up to 24 months, exhibited reduced body weight and changes in liver, spleen and kidney weights. No adverse histologic. haematologic, biochemical or urinological effects were seen. The "no-effect" level was 150 mg/kg/day. No significant teratogenic or foetotoxic effects were observed in the off-spring of rats and mice exposed to the neutral sodium salt, by gavage. No maternal toxicity was observed at any level. No adverse treatment related effects or reproductive parameters and no pathological or histopathological lesions were observed in either parental animals or pups following dietary exposure of the solid active acid at various times in the mating and birth cycle for three generations.  Rats fed on ethylenediamine(methylenephosphonic acid (EDTMP) (300 mg/kg daily for 10 weeks) before mating and up to the end of the mating period, showed reduced body weights, defects in dental enamel on the incisors and significantly reduced liver weights. In an ongoing study, several rats treated with EDTMP (50-333 mg/kg/day) died during the first twelve months and were seen to have osteosarcomas with metastases. Other adverse effects of EDTMP treatment included increased white blood cell counts in mice, anaemia and reduction in erythrocytes, haemoglobin, haematocrit, serum cholesterol, total serum protein and globulin, in rats.  In a one-generation reproductive study the off-spring of rats, fed up to 3000 ppm DTPMPA (diethylenetriaminepentakis(methylenephosphonic acid)), showed no adverse effects although there was a slight decrease in birth weights.  Chronic exposure to tin dusts and fume can result in substantial amounts being deposited in the lungs and result in reduced lung function and difficulty breathing.