Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

PRODUCT NAME

ZEARANOL

NFPA

PRODUCT USE

Zearanol is used as a growth promoter in beef cattle, feedlot lambs and suckling beef
calves.

SYNONYMS

C18-H26-O5, "1H-2-benzoxyacyclotetradecin-1-one, ", "1H-2-benzoxyacyclotetradecin-1-one,
", "3, 4, 5, 6, 7, 8, 9, 10, 11, 12-decahydro-7, 14, 16-trihydroxy-3-methyl-, (3S, 7X)-",
"3, 4, 5, 6, 7, 8, 9, 10, 11, 12-decahydro-7, 14, 16-trihydroxy-3-methyl-, (3S, 7X)-",
"6-(6, 10-dihydroxyundecyl)-beta-resorcylic acid, mu-lactone", "6-(6, 10-
dihydroxyundecyl)-beta-resorcylic acid, mu-lactone", Frideron, MK-188, P1496, Ralabol,
Ralgro, Ralone, Zearalanol, Zeranol, anabolic

Section 2 - HAZARDS IDENTIFICATION

CANADIAN WHMIS SYMBOLS

None

EMERGENCY OVERVIEW

RISK

POTENTIAL HEALTH EFFECTS

ACUTE HEALTH EFFECTS

SWALLOWED

  Although ingestion is not thought to produce harmful effects, the material may still be damaging to the health of the individual following ingestion, especially where pre-  existing organ (e.g. liver, kidney) damage is evident. Present definitions of harmful or toxic substances are generally based on doses producing mortality (death) rather than those producing morbidity (disease, ill-health). Gastrointestinal tract discomfort may produce nausea and vomiting. In an occupational setting however, ingestion of insignificant quantities is not thought to be cause for concern.  Considered an unlikely route of entry in commercial/industrial environments.  

EYE

  Although the material is not thought to be an irritant, direct contact with the eye may produce transient discomfort characterized by tearing or conjunctival redness (as with windburn).  

SKIN

  The material is not thought to produce adverse health effects or skin irritation following contact (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable gloves be used in an occupational setting.  

INHALED

  The material is not thought to produce adverse health effects or irritation of the respiratory tract (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable control measures be used in an occupational setting.  Persons with impaired respiratory function, airway diseases and conditions such as emphysema or chronic bronchitis, may incur further disability if excessive concentrations of particulate are inhaled.  

CHRONIC HEALTH EFFECTS

  Principal routes of exposure are usually by skin contact/absorption and inhalation of generated dust.  Mycooestrogens are dietary oestrogens of fungal origin. Cereals stored under moist conditions can become contaminated by moulds that produce mycooestrogens. Both domestic livestock and humans consume significant quantities of mycooestrogen following consumption of contaminated rice, corn, wheat and barley.In common with other oestrogen mimics, mycooestrogens may alter fertility and produce reproductive deficits in farm animals and mammals.Zearalenone is held responsible for the fertility problems and oestrogenisation of farm animals, in particular pigs, observed after feeding of contaminated hay or corn ("mould corn disease").