Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

PRODUCT NAME

ZIRCONIUM ACETYLACETONATE

NFPA

PRODUCT USE

Tetrachelate used asa crosslinking agent for polyol, polyester and polyalkoxy resins;
grease and lubricant additive; catalyst. Regeant

SYNONYMS

C20-H28-O8-Zr, [CH3COCH=C(O-)CH3]4Zr, "2, 4-pentanedione, zirconium complex", "2, 4-
pentanedione, zirconium complex", "zirconium, acetyl-, acetonate", "zirconium
acetoacetonate", "zirconium, tetrakis(2, 4-pentanedionato-O, O')-",
tetrakis(acetylacetonato)zirconium, tetrakis(pentanedionato)zirconium, "zirconium
acetylacetone chelate", "zirconium tetrakis(acetylacetonate)"

Section 2 - HAZARDS IDENTIFICATION

CANADIAN WHMIS SYMBOLS

EMERGENCY OVERVIEW

RISK

POTENTIAL HEALTH EFFECTS

ACUTE HEALTH EFFECTS

SWALLOWED

  Accidental ingestion of the material may be damaging to the health of the individual.  Because inorganic zirconium is poorly absorbed from the digestive tract, acute oral toxicity is low. Injection is much more dangerous, causing progressive depression until death.  At sufficiently high doses the material may be neurotoxic(i.e. poisonous to the nervous system).  

EYE

  Although the material is not thought to be an irritant, direct contact with the eye may cause transient discomfort characterized by tearing or conjunctival redness (as with windburn). Slight abrasive damage may also result. The material may produce foreign body irritation in certain individuals.  

SKIN

  Skin contact is not thought to have harmful health effects, however the material may still produce health damage following entry through wounds, lesions or abrasions.  There is some evidence to suggest that this material can cause inflammation of the skin on contact in some persons.  The external application of zirconium can cause nodules in the skinof the armpits.  Open cuts, abraded or irritated skin should not be exposed to this material.  2,4-Pentadione may produce contact dermatitis or urticaria. Prolonged contact with 2,4-  pentanedione may produce severe discomfort or pain, redness and swelling and corrosion, ulceration and development of fissures. The inflamed area may show bleeding.  Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may produce systemic injury with harmful effects. Examine the skin prior to the use of the material and ensure that any external damage is suitably protected.  

INHALED

  The material is not thought to produce either adverse health effects or irritation of the respiratory tract following inhalation (as classified using animal models). Nevertheless, adverse effects have been produced following exposure of animals by at least one other route and good hygiene practice requires that exposure be kept to a minimum and that suitable control measures be used in an occupational setting.  Zirconium workers exposed to fume for 1-5 years showed no abnormalities due to zirconium. Animal studies also reveal a low order of hazard from inhaled zirconium.  At sufficiently high doses the material may be neurotoxic(i.e. poisonous to the nervous system).  

CHRONIC HEALTH EFFECTS

  Limited evidence suggests that repeated or long-term occupational exposure may produce cumulative health effects involving organs or biochemical systems.  There is limited evidence that, skin contact with this product is more likely to cause a sensitization reaction in some persons compared to the general population.  Long term exposure to high dust concentrations may cause changes in lung function i.e. pneumoconiosis; caused by particles less than 0.5 micron penetrating and remaining in the lung. Prime symptom is breathlessness; lung shadows show on X-ray.  Zirconium can accumulate in the spleen. Oral administration has not beenshown to cause any ill effects.  Repeated overexposure to 200 ppm 2,4-pentanedione vapor may result in inflammation of the nasal mucosa. Higher concentrations may produce central nervous system effects, and immune system and bone marrow deficits. Recurrent exposure to high concentrations of the 2,4-pentadione vapor (~650 ppm) produces lethal degenerative lesions in the central nervous system and thymus. Exposure in pregnancy can damage to fetus.