Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

PRODUCT NAME

P-METHOXYPHENYL GLYCIDYL ETHER

NFPA

PRODUCT USE

Intermediate. Intermediate

SYNONYMS

C10-H12-O3, "benzene, 1-(2, 3-epoxypropoxy)-4-methoxy-", "benzene, 1-(2, 3-
epoxypropoxy)-4-methoxy-", "anisole, p-(2, 3-epoxypropoxy)-", "anisole, p-(2, 3-
epoxypropoxy)-", "2, 3-ethoxypropyl-4-methoxyphenyl ether", "2, 3-ethoxypropyl-4-
methoxyphenyl ether", "glycidyl p-methoxyphenyl ether", "glycidyl p-methoxyphenyl ether",
"glycidyl 4-methoxyphenyl ether", "glycidyl 4-methoxyphenyl ether", ((4-
methoxyphenoxy)methyl)oxirane, 2-(p-methoxyphenoxymethyl)oxirane, 2-(p-
methoxyphenoxymethyl)oxirane, "2, 3-epoxypropyl 4-methoxyphenyl ether", "2, 3-epoxypropyl
4-methoxyphenyl ether", "oxirane, ((4-methoxyphenoxy)methyl)-"

Section 2 - HAZARDS IDENTIFICATION

CANADIAN WHMIS SYMBOLS

EMERGENCY OVERVIEW

RISK

May form explosive peroxides.
May cause SENSITIZATION by skin contact.
Limited evidence of a carcinogenic effect.
Possible risk of irreversible effects.
Irritating to eyes, respiratory system and skin.

POTENTIAL HEALTH EFFECTS

ACUTE HEALTH EFFECTS

SWALLOWED

  The material has NOT been classified as "harmful by ingestion". This is because of the lack of corroborating animal or human evidence. The material may still be damaging to the health of the individual, following ingestion, especially where pre-existing organ (e.g. liver, kidney) damage is evident. Present definitions of harmful or toxic substances are generally based on doses producing mortality (death) rather than those producing morbidity (disease, ill-health). Gastrointestinal tract discomfort may produce nausea and vomiting. In an occupational setting however, unintentional ingestion is not thought to be cause for concern.  

EYE

  This material can cause eye irritation and damage in some persons.  

SKIN

  This material can cause inflammation of the skin oncontact in some persons.  The material may accentuate any pre-existing dermatitis condition.  Skin contact is not thought to have harmful health effects, however the material may still produce health damage following entry through wounds, lesions or abrasions.  Open cuts, abraded or irritated skin should not be exposed to this material.  Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may produce systemic injury with harmful effects. Examine the skin prior to the use of the material and ensure that any external damage is suitably protected.  

INHALED

  The material can cause respiratory irritation in some persons. The body's response to such irritation can cause further lung damage.  Persons with impaired respiratory function, airway diseases and conditions such as emphysema or chronic bronchitis, may incur further disability if excessive concentrations of particulate are inhaled.  

CHRONIC HEALTH EFFECTS

  There has been concern that this material can cause cancer or mutations, but there is not enough data to make an assessment.  Long-term exposure to respiratory irritants may result in disease of the airways involving difficult breathing and related systemic problems.  Skin contact with the material is more likely to cause a sensitization reaction in some persons compared to the general population.  Exposure to the material may result in a possible risk of irreversible effects. The material may produce mutagenic effects in man. This concern is raised, generally, on the basis ofappropriate studies using mammalian somatic cells in vivo. Such findings are often supported by positive results from in vitro mutagenicity studies.  Limited evidence suggests that repeated or long-term occupational exposure may produce cumulative health effects involving organs or biochemical systems.  Glycidyl ethers can cause genetic damage and cancer.  There is some evidence that inhaling this product is more likely to cause a sensitization reaction in some persons compared to the general population.  Respiratory sensitization may result in allergic/asthma like responses; from coughing and minor breathing difficulties to bronchitis with wheezing, gasping.