LEAD SALICYLATE
Flammability | 1 | |
Toxicity | 2 | |
Body Contact | 2 | |
Reactivity | 1 | |
Chronic | 3 | |
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4 |
Stabiliser or co- stabiliser for vinyl compounds requiring good light stability; modifier
for explosives.
C14-H10-O6-Pb, Pb(HO-C6H4-CO2)2, Pb(C7H5O3)2, "lead beta-resorcylate", "salicylic acid,
lead (2+) salt(2:1)", "benzoic acid, 2-hydroxy-, lead(2+) salt(2:1)", "benzoic acid, 2-
hydroxy-, lead(2+) salt(2:1)"
Danger of cumulative effects.
May cause harm to the unborn child.
Possible risk of impaired fertility.
Harmful by inhalation and if swallowed.
Very toxic to aquatic organisms, may cause long- term adverse effects in the
aquatic environment.
Accidental ingestion of the material may be harmful; animal experiments indicate that ingestion of less than 150 gram may be fatal or may produce serious damage to the health of the individual. High oral doses of salicylates, such as aspirin, may cause a mild burning pain in the throat and stomach, causing vomiting. This is followed (within hours) by deep, rapid breathing, tiredness, nausea and further vomiting, thirst and diarrhea. The central nervous system is first stimulated, and then depression from failure occurs. Stimulation produces vomiting, hyperventilation, headache, ringing in the ears, confusion, behavior and mood changes, and generalized convulsions. Respiratory failure and cardiovascular collapse can result in death. There may also be sweating, skin eruptions, internal bleeding, kidney failure and inflamed pancreas. There may be bloody stools, purple skin spots or blood in the vomit. Many of these symptoms are due to disturbances in blood chemistry. A dose of 300 mg/kg can cause serious effects while 500 mg/kg can be lethal.
Although the material is not thought to be an irritant, direct contact with the eye may produce transient discomfort characterized by tearing or conjunctival redness (as with windburn).
The material is not thought to produce adverse health effects or skin irritation following contact (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable gloves be used in an occupational setting. Solution of material in moisture on the skin, or perspiration, mayincrease irritant effects. Open cuts, abraded or irritated skin should not be exposed to this material. Toxic effects may result from skin absorption.
The material is not thought to produce respiratory irritation (as classified using animal models). Nevertheless inhalation of the material, especially for prolonged periods, may produce respiratory discomfort and occasionally, distress. Persons with impaired respiratory function, airway diseases and conditions such as emphysema or chronic bronchitis, may incur further disability if excessive concentrations of particulate are inhaled.
Ample evidence exists that developmental disorders are directlycaused by human exposure to the material.
Principal routes of exposure are by accidental skin and eye contact andinhalation of generated dusts. Lead can cross the placenta, and cause miscarriage, stillbirths and birth defects. Exposure before birth can cause mental retardation, behavioral disorders and infant death. Lead can also cause reduced sex drive, impotence, sterility and damage the sperm of males, increasing the potential for birth defects. Periods in women can also be affected. Lead can accumulate in the skeleton for a very long time. Chronic exposure to salicylates produce problems with metabolism, central system disturbances, or kidney damage. Those with pre-existing damage to the eye, skin or kidney are especially at risk. Hypersensitive reactions can occur, especially in people with asthma. These symptoms include itchy wheals and other skin eruptions, an inflamed nose, shortness of breath and serious narrowing of the airways (which can even cause death). Chronic exposure to parabens by skin contact, ingestion or injection can cause hypersensitive reactions. There may be cross-sensitivity between different species, so people can be develop allergic symptoms if they were sensitized by other chemicals. Symptoms include acute narrowing of the airways, hives (itchy wheal), swelling, running nose and blurred vision. There may be anaphylactic shock and rash.