Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

PRODUCT NAME

KEY NO-DOZ PLUS

NFPA

PRODUCT USE

Used to help relieve mental fatigue, drowsiness and general inertia to promote a bright
and alert state. Each tablet contains 100 mg caffeine. Dosage: 1 tablet. Repeated dosage
should not be taken under 3 hours. No more than 5 tablets to be taken within 24 hours.
Dose should be reduced if tea, coffee or cola beverages are also taken. As a comparison,
approx. caffeine content of various beverages per 6 oz cup: brewed coffee: 100 to 150 mg;
`instant' coffee: 60 to 80 mg; decaffeinated coffee 3 to 5 mg; tea 40 to 100 mg; cola
drinks: 17 to 55 mg. Do not administer to children under 12 years of age.

SYNONYMS

"No-Doze (misspelling) caffeine tablets wake up alertness tablets"

Section 2 - HAZARDS IDENTIFICATION

CANADIAN WHMIS SYMBOLS

EMERGENCY OVERVIEW

RISK

POTENTIAL HEALTH EFFECTS

ACUTE HEALTH EFFECTS

EYE

  Not applicable.  

INHALED

  Inhalation may produce health damage*.  Not applicable.  

CHRONIC HEALTH EFFECTS

  Principal routes of exposure are usually by accidental ingestion.  Excessive consumption of beverages containing caffeine, termed caffeinism,  may cause headaches, irritability and symptoms of anxiety neurosis.  The U.S. Food and Drug Administration has proposed removal of caffeine from  its `generally recognised as safe' list and is gathering additional  information. Concerns with excessive use include possible reproductive  effects to foetal craniofacial area, musculoskeletal system, possible  bladder cancer (2 separate epidemiological studies), myocardial  infarction and, to lesser degrees, constipation, palpitations, shortness  of breath and depressed mental state.  Women with a high daily intake of caffeine may have a higher incidence of  abortion and prematurity.  McGee reports a 19 year old woman with abdominal cramps, semicomatose, with  shallow irregular breathing. She developed ventricular fibrillation and  died in 3 hours. At autopsy, a blood caffeine level was 0.181 mg/ml. She  had been ingesting over-the-counter diet pills and was estimated to have  ingested 18 grams of caffeine.