KEMFAST JC5A
Flammability | 2 | |
Toxicity | 2 | |
Body Contact | 3 | |
Reactivity | 1 | |
Chronic | 4 | |
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4 |
Used according to manufacturer' s directions.
Irritating to skin.
Risk of serious damage to eyes.
May cause CANCER.
May cause SENSITIZATION by skin contact.
Harmful by inhalation and if swallowed.
Flammable.
Very toxic to aquatic organisms, may cause long- term adverse effects in the
aquatic environment.
Accidental ingestion of the material may be harmful; animal experiments indicate that ingestion of less than 150 gram may be fatal or may produce serious damage to the health of the individual. Swallowing of the liquid may cause aspiration into the lungs with the risk of chemical pneumonitis; serious consequences may result. (ICSC13733). Chromate salts are corrosive and produce cellular damage to tissue. Ingestion may produce inflammation of the digestive tract, nausea, vomiting and abdominal pain. Chromates cause kidney damage and blood cell damage.
If applied to the eyes, this material causes severe eye damage.
This material can cause inflammation of the skin oncontact in some persons. The material may accentuate any pre-existing dermatitis condition. Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may produce systemic injury with harmful effects. Examine the skin prior to the use of the material and ensure that any external damage is suitably protected.
There is some evidence to suggest that the material can cause respiratory irritation in some persons. The body's response to such irritation can cause further lung damage. Headache, fatigue, lassitude, irritability and gastrointestinal disturbances (e.g., nausea, anorexia and flatulence) are the most common symptoms of xylene overexposure. Injury to the heart, liver, kidneys and nervous system has also been noted amongst workers. Transient memory loss, renal impairment, temporary confusion and some evidence of disturbance of liver function was reported in three workers overcome by gross exposure to xylene (10000 ppm). One worker died and autopsy revealed pulmonary congestion, oedema and focal alveolar haemorrhage. Volunteers inhaling xylene at 100 ppm for 5 to 6 hours showed changes in manual coordination reaction time and slight ataxia. Tolerance developed during the workweek but was lost over the weekend. Physical exercise may antagonise this effect. Xylene body burden in humans exposed to 100 or 200 ppm xylene in air depends on the amount of body fat with 4% to 8% of total absorbed xylene accumulating in adipose tissue. Xylene is a central nervous system depressant. Welding or flame cutting of metals with chromate pigmented primers or coatings may result in inhalation of highly toxic chromate fumes. Exposures may be significant in enclosed or poorly ventilated areas.
Skin contact with the material is more likely to cause a sensitization reaction in some persons compared to the general population. There is sufficient evidence to suggest that this materialdirectly causes cancer in humans. Limited evidence suggests that repeated or long-term occupational exposure may produce cumulative health effects involving organs or biochemical systems. There is some evidence that human exposure to the material may result in developmental toxicity. This evidence is based on animal studies where effects have been observed in the absence of marked maternal toxicity, or at around the same dose levels as other toxic effects but which are not secondary non-specific consequences of the other toxic effects. Chromium(III) is an essential trace mineral. Chronic exposure to chromium(III) irritates the airways, malnourishes the liver and kidneys, causes fluid in the lungs, and adverse effects on white blood cells, and also increases the risk of developing lung cancer. Chromium (VI) can irritate the skin, eyes and airways. Allergic reactions can involve both the skin and airways, and the compounds can diminish taste and smell, discolor the skin and eyes, cause blood disorders and damage the liver, kidneys, digestive tract and lungs. It predisposes humans to cancers of the respiratory tract and digestive system. Ulceration to the skin can occur, and, chromium(VI) is one of the most allergenic substances known. Prolonged or repeated contact with xylenes may cause defatting dermatitis with drying and cracking. Chronic inhalation of xylenes has been associated with central nervous system effects, loss of appetite, nausea, ringing in the ears, irritability, thirst anaemia, mucosal bleeding, enlarged liver and hyperplasia. Exposure may produce kidney and liver damage. In chronic occupational exposure, xylene (usually mix ed with other solvents) has produced irreversible damage to the central nervous system and ototoxicity (damages hearing and increases sensitivity to noise), probably due to neurotoxic mechanisms. Industrial workers exposed to xylene with a maximum level of ethyl benzene of 0.06 mg/l (14 ppm) reported headaches and irritability and tired quickly. Functional nervous system disturbances were found in some workers employed for over 7 years whilst other workers had enlarged livers. Xylene has been classed as a developmental toxin in some jurisdictions. Small excess risks of spontaneous abortion and congenital malformation were reported amongst women exposed to xylene in the first trimester of pregnancy. In all cases, however, the women were also been exposed to other substances. Evaluation of workers chronically exposed to xylene has demonstrated lack of genotoxicity. Exposure to xylene has been associated with increased risks of haemopoietic malignancies but, again, simultaneous exposure to other substances (including benzene) complicates the picture. A long-term gavage study to mixed xylenes (containing 17% ethyl benzene) found no evidence of carcinogenic activity in rats and mice of either sex. Exposure to the material for prolonged periods may cause physical defects in the developing embryo (teratogenesis). Barium compounds may cause high blood pressure, airway irritation and damage the liver, spleen and bone marrow. Prolonged exposure may cause a lung inflammation and scarring. Symptoms of this include a worsening dry cough, shortness of breath on exertion, increased chest expansion and weakness. Stringy phlegm in the cough appears later, with more difficulty in breathing and a further loss of lung capacity. Barium sulfate does not cause permanent scarring of the lungs.