L-FENCHONE
Flammability | 2 | |
Toxicity | 2 | |
Body Contact | 2 | |
Reactivity | 1 | |
Chronic | 0 | |
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4 |
Extracted from oil of thuja. Used as a flavouring and in perfumery. Therapeutically useful
as a counter- irritant.
C10-H16-O, "(1R)-1, 3, 3-trimethyl-2-norbornanone", "(1R)-1, 3, 3-trimethyl-2-
norbornanone", "l-1, 3, 3-trimethylbicyclo[2.2.1]heptan-2-one", "l-1, 3, 3-
trimethylbicyclo[2.2.1]heptan-2-one", "(-)-1, 3, 3-trimethyl-2-norcamphanone", "(-)-1, 3,
3-trimethyl-2-norcamphanone", "natural product", "extracted from oil of thuja"
Flammable.
Although ingestion is not thought to produce harmful effects, the material may still be damaging to the health of the individual following ingestion, especially where pre- existing organ (e.g. liver, kidney) damage is evident. Present definitions of harmful or toxic substances are generally based on doses producing mortality (death) rather than those producing morbidity (disease, ill-health). Gastrointestinal tract discomfort may produce nausea and vomiting. In an occupational setting however, ingestion of insignificant quantities is not thought to be cause for concern. Considered an unlikely route of entry in commercial/industrial environments. Essential oils cause mild irritation of the mouth if taken orally, causing more saliva to be produced and a warm feeling. Large amounts affect the digestive system causing nausea, vomiting and diarrhea. Sometimes urination may be affected, causing difficulty or pain in urinating, reduced urine output, blood in the urine, unconsciousness and shallow breathing. Lung swelling and inflammation are possible complications. Stupor, excitement and respiratory failure may result, as well as convulsions; the central nervous system may either be depressed or stimulated. The kidneys may be damaged, and swelling and severe clogging can occur in the lungs, skin and kidneys. Essential oils increase the rate of miscarriage, but in low doses do not usually cause an abortion.
Although the material is not thought to be an irritant, direct contact with the eye may produce transient discomfort characterized by tearing or conjunctival redness (as with windburn).
The material is not thought to produce adverse health effects or skin irritation following contact (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable gloves be used in an occupational setting. The liquid may produce skin discomfort following prolonged contact. Defatting and/or drying of the skin may lead to dermatitis. Essential oils irritate the skin and redden it, causing at first warmth and smarting, followed by some local loss of sensation. They have been used to treat chronic inflammatory conditions and to relieve neuralgia and rheumatic pain. Care should be taken to avoid blistering; these oils may also produce sensitization.
There is some evidence to suggest that this material, if inhaled, can irritate the throat and lungs of some persons. Although inhalation is not thought to produce harmful effects, the material may still produce health damage, especially where pre-existing organ (e.g. liver, kidney) damage is evident. Present definitions of harmful or toxic substances are generally confined to doses producing mortality (death) rather than those producing morbidity (disease, ill- health). Inhalation hazard is increased at higher temperatures. Acute effects from inhalation of high concentrations of vapor may be nose, throat and chest irritation with coughing, sneezing and possible nausea.
Principal routes of exposure are usually by skin contact/absorption and inhalation of vapor. Prolonged or continuous skin contact with the liquid may cause defatting with drying, cracking, irritation and dermatitis following. As with any chemical product, contact with unprotected bare skin; inhalation of vapor, mist or dust in work place atmosphere; or ingestion in any form, should be avoided by observing good occupational work practice.