Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

PRODUCT NAME

HAARMANN & REIMER 740015 GRAPEFRUIT V1306 RB 41637RB

NFPA

PRODUCT USE

Fragrance Not for personal use in this form or concentration. For manufacturing use only.

Section 2 - HAZARDS IDENTIFICATION

CANADIAN WHMIS SYMBOLS

EMERGENCY OVERVIEW

RISK

Contact with combustible material may cause fire.
Irritating to eyes.
HARMFUL - May cause lung damage if swallowed.
Flammable.
Harmful to aquatic organisms, may cause long- term adverse effects in the
aquatic environment.

POTENTIAL HEALTH EFFECTS

ACUTE HEALTH EFFECTS

SWALLOWED

  Accidental ingestion of the material may be damaging to the health of the individual.  Swallowing of the liquid may cause aspiration into the lungs with the risk of chemical pneumonitis; serious consequences may result. (ICSC13733).  Exposure to aldehydes causes neurological symptoms such as headache, drowsiness, dizziness, seizures, depression and coma. Cardiovascular involvement may result in increased heart rate, collapse and low blood pressure; respiratory effects include throat spasms, irritation, difficulty swallowing, pulmonary edema and an asthma-like condition. Gastrointestinal signs include nausea, blood in vomit, diarrhea, ulcers and abdominal pain. Massive exposures may damage the kidney and liver.  Heparin, coumarin and indan-1,3-dione derivatives are used to kill rodents and to prevent blood clotting. They block the synthesis of prothrombin by antagonizing vitamin K. They are safe in normal use but with high does or prolonged use, they can cause bleeding accidents, especially in sensitive persons. Symptoms of poisoning include nausea and vomiting; effects may be delayed for days. Other symptoms include bleeding gums, easy bruising, blood in the urine and excessive bleeding from minor wounds. Severe poisonings can cause shock, coma and death.  Essential oils cause mild irritation of the mouth if taken orally, causing more saliva to be produced and a warm feeling. Large amounts affect the digestive system causing nausea, vomiting and diarrhea. Sometimes urination may be affected, causing difficulty or pain in urinating, reduced urine output, blood in the urine, unconsciousness and shallow breathing. Lung swelling and inflammation are possible complications. Stupor, excitement and respiratory failure may result, as well as convulsions; the central nervous system may either be depressed or stimulated. The kidneys may be damaged, and swelling and severe clogging can occur in the lungs, skin and kidneys. Essential oils increase the rate of miscarriage, but in low doses do not usually cause an abortion.  

EYE

  There is evidence that material may produce eye irritation in some persons and produce eye damage 24 hours or more after instillation. Severe inflammation may be expected with pain. There may be damage to the cornea. Unless treatment is prompt and adequate there may be permanent loss of vision. Conjunctivitis can occur following repeated exposure.  

SKIN

  There is some evidence to suggest that the material may cause mild but significant inflammation of the skin either following direct contact or after a delay of some time. Repeated exposure can cause contact dermatitis which is characterized by redness, swelling and blistering.  Skin contact is not thought to have harmful health effects, however the material may still produce health damage following entry through wounds, lesions or abrasions.  Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may produce systemic injury with harmful effects. Examine the skin prior to the use of the material and ensure that any external damage is suitably protected.  Essential oils irritate the skin and redden it, causing at first warmth and smarting, followed by some local loss of sensation. They have been used to treat chronic inflammatory conditions and to relieve neuralgia and rheumatic pain. Care should be taken to avoid blistering; these oils may also produce sensitization.  d-limonene causes moderate irritation to skin including redness and swelling. Sometimes there are delayed hemorrhagic lesions.  Following contact with plants that produce furocoumarins and direct sunlight, a severe, painful reaction can occur, with blisters. This reaction occurs 6 to 24 hours following exposure. Important plants include limes, lemons, figs, celery, carrots, parsley, parsnip,  dill, rue, bergamot and the "gas" plant. Workers are susceptible as soon as they are exposed to sunlight. Fungal parasites may increase the amount of furocoumarins and hence the severity of the reaction.  

INHALED

  There is some evidence to suggest that the material can cause respiratory irritation in some persons. The body's response to such irritation can cause further lung damage.  Inhalation of high concentrations of gas/vapor causes lung irritation with coughing and nausea, central nervous depression with headache and dizziness, slowing of reflexes, fatigue and inco-ordination.  Inhalation of vapors or aerosols (mists, fumes), generated by the material during the course of normal handling, may produce severely toxic effects; these may be fatal.  Inhalation of essential oil volatiles may cause dizziness, rapid, shallow breathing, increased heart rate, respiratory irritation, loss of consciousness or convulsions. Urination may stop, and there may be swelling and inflammation of the lungs.  

CHRONIC HEALTH EFFECTS

  There has been some concern that this material can cause cancer or mutations but there is not enough data to make an assessment.  There is limited evidence that, skin contact with this product is more likely to cause a sensitization reaction in some persons compared to the general population.  d-Limonene may cause damage to and growths in the kidney.These growths can progress to cancer.  In one study with citrus oils, the authors concluded that a common component was capable of promoting skin tumor development in previously initiated mice. Roe F.J.C. Pierce W.E.I.; Jnl Nat Cancer Inst. 24, 1389-1403, 1960.  Sensitization may result in allergic dermatitis responses includingrash, itching, hives or swelling of extremities.