Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

PRODUCT NAME

KCH KERAMCHEMIE KERATEX HARDENER

NFPA

PRODUCT USE

Reactive isocyanate is used as a primer and bonding agent on surfaces with difficult
adhesion. Used to bond rubber to metal. Requires use of control procedures and protective
gear if spray applied or if heated. [MANUFACTURER]

SYNONYMS

"triphenylmethane diisocyanate", "isocyanate curing agent", hardener, "polyfunctional
aromatic triisocyanate", 40023, 2950-40023

Section 2 - HAZARDS IDENTIFICATION

CANADIAN WHMIS SYMBOLS

EMERGENCY OVERVIEW

RISK

Harmful if swallowed.
Irritating to skin.
May cause SENSITIZATION by skin contact.
Limited evidence of a carcinogenic effect.
Toxic to aquatic organisms, may cause long- term adverse effects in the aquatic
environment.

POTENTIAL HEALTH EFFECTS

ACUTE HEALTH EFFECTS

SWALLOWED

  Accidental ingestion of the material may be harmful; animal experiments indicate that ingestion of less than 150 gram may be fatal or may produce serious damage to the health of the individual.  Ingestion may result in nausea, pain, vomiting. Vomit entering the lungs by aspiration may cause potentially lethal chemical pneumonitis.  Considered an unlikely route of entry in commercial/industrial environments.  

EYE

  There is some evidence to suggest that this material can causeeye irritation and damage in some persons.  The material may produce moderate eye irritation leading to inflammation. Repeated or prolonged exposure to irritants may produce conjunctivitis.  

SKIN

  This material can cause inflammation of the skin oncontact in some persons.  Skin contact is not thought to have harmful health effects, however the material may still produce health damage following entry through wounds, lesions or abrasions.  The material may cause severe skin irritation after prolonged or repeated exposure and may produce on contact skin redness, swelling, the production of vesicles, scaling and thickening of the skin. Repeated exposures may produce severe ulceration.  Toxic effects may result from skin absorption.  Open cuts, abraded or irritated skin should not be exposed to this material.  Sensitization may result in allergic dermatitis responses includingrash, itching, hives or swelling of extremities.  Sensitization reactions may appear suddenly after repeatedsymptom free exposures.  The material may accentuate any pre-existing dermatitis condition.  

INHALED

  The material is not thought to produce adverse health effects or irritation of the respiratory tract (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable control measures be used in an occupational setting.  The vapor/mist may be highly irritating to the upper respiratory tract and lungs; the response may be severe enough to produce bronchitis and pulmonary edema. Possible neurological symptoms arising from isocyanate exposure include headache, insomnia, euphoria, ataxia, anxiety neurosis, depression and paranoia. Gastrointestinal disturbances are characterized by nausea and vomiting. Pulmonary sensitization may produce asthmatic reactions ranging from minor breathing difficulties to severe allergic attacks; this may occur following a single acute exposure or may develop without warning for several hours after exposure. Sensitized people can react to very low doses, and should not be allowed to work in situations allowing exposure to this material. Continued exposure of sensitized persons may lead to possible long term respiratory impairment.Inhalation hazard is increased at higher temperatures.  Inhalation exposure may cause susceptible individuals to show change in heart beat rhythm i.e. cardiac arrhythmia. Exposures must be terminated.  Anesthetics and narcotic effects (with dulling of senses and odor fatigue) are a consequence of exposure to chlorinated solvents.  Individual response varies widely; odor may not be considered objectionable at levels which quickly induce central nervous system effects. High vapor concentrations may give a feeling of euphoria. This may result in reduced responses, followed by rapid onset of unconsciousness, possible respiratory arrest and death.  Inhalation of vapor may aggravate a pre-existing respiratory condition such as asthma, bronchitis, emphysema.  

CHRONIC HEALTH EFFECTS

  There has been concern that this material can cause cancer or mutations, but there is not enough data to make an assessment.  Skin contact with the material is more likely to cause a sensitization reaction in some persons compared to the general population.  

  Principal routes of exposure are usually by inhalation of vapor/spray mist and skin contact with the material.  Prolonged or repeated skin contact may cause drying with cracking,irritation and possible dermatitis following.  Sensitization may give severe responses to very low levels of exposure, i.e. hypersensitivity. Sensitized persons should not be allowed to work in situations where exposure may occur.  Dichloromethane is stored in body fat and metabolized to carbon monoxide, which reduces the oxygen carrying capacity of blood.  Inhalation exposure may cause susceptible individuals to show change in heart beat rhythm i.e. cardiac arrhythmia. Exposures must be terminated.  Effects may be potentiated by alcohol consumption and effort.  Isocyanate component has low vapour pressure at ambient temperatures.  Methylene chloride causes liver and kidney damage in animals and this  justifies consideration before exposing persons with a history of impaired  liver function and/or renal disorders to long term exposure.