Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

PRODUCT NAME

OCTADECYLTRIMETHOXYSILANE

NFPA

PRODUCT USE

Silylating agent.

SYNONYMS

C21-H46-O3-Si, (CH3O)3SiCH2(CH2)17CH3, "octadecyl trimethoxysilane", "silylating agent"

Section 2 - HAZARDS IDENTIFICATION

CANADIAN WHMIS SYMBOLS

EMERGENCY OVERVIEW

RISK

Flammable.

POTENTIAL HEALTH EFFECTS

ACUTE HEALTH EFFECTS

SWALLOWED

  Although ingestion is not thought to produce harmful effects, the material may still be damaging to the health of the individual following ingestion, especially where pre-  existing organ (e.g. liver, kidney) damage is evident. Present definitions of harmful or toxic substances are generally based on doses producing mortality (death) rather than those producing morbidity (disease, ill-health). Gastrointestinal tract discomfort may produce nausea and vomiting. In an occupational setting however, ingestion of insignificant quantities is not thought to be cause for concern.  Ingestion may result in nausea, pain, vomiting. Vomit entering the lungs by aspiration may cause potentially lethal chemical pneumonitis.  Methanol may produce a burning or painful sensation in the mouth, throat, chest, and stomach. This may be accompanied by nausea, vomiting, headache, dizziness, shortness of breath, weakness, fatigue, leg cramps, restlessness, confusion, drunken behavior, visual disturbance, drowsiness, coma and death. These symptoms may not occur until several hours after exposure. Visual impairment produces blurring, double vision, color distortion, reduced visual field, and blindness. In higher doses, the liver, kidney, heart and muscle can all be damaged. 10mL can cause blindness, and 60-200mL will cause death in adults.  

EYE

  Although the material is not thought to be an irritant, direct contact with the eye may produce transient discomfort characterized by tearing or conjunctival redness (as with windburn).  

SKIN

  The material is not thought to produce adverse health effects or skin irritation following contact (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable gloves be used in an occupational setting.  The liquid may produce skin discomfort following prolonged contact. Defatting and/or drying of the skin may lead to dermatitis.  The material may accentuate any pre-existing skin condition.  

INHALED

  Inhalation may produce health damage*.  The material is not thought to produce respiratory irritation (as classified using animal models). Nevertheless inhalation of the material, especially for prolonged periods, may produce respiratory discomfort and occasionally, distress.  Inhalation of vapor may aggravate a pre-existing respiratory condition.  Inhalation hazard is increased at higher temperatures.  Inhalation of vapor may result in nausea, headache.  

CHRONIC HEALTH EFFECTS

  Principal routes of exposure are by accidental skin and eye contact and by inhalation of vapors especially at higher temperatures.  Hydrolysis under humid conditions may expose individuals to methanol  vapour.  Long-term exposure to methanol vapor, at concentrations exceeding 3000 ppm, may produce cumulative effects characterized by gastrointestinal disturbances (nausea, vomiting), headache, ringing in the ears, insomnia, trembling, unsteady gait, vertigo, conjunctivitis and clouded or double vision. Liver and/or kidney injury may also result. Some individuals show severe eye damage following prolonged exposure to 800 ppm of the vapor.