Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

PRODUCT NAME

QUAKER CHEMICAL QUINTOLUBRIC A720

NFPA

PRODUCT USE

Fire resistant hydraulic fluid.

SYNONYMS

"hydraulic fluid"

Section 2 - HAZARDS IDENTIFICATION

CANADIAN WHMIS SYMBOLS

EMERGENCY OVERVIEW

RISK

HARMFUL - May cause lung damage if swallowed.
Irritating to eyes and skin.

POTENTIAL HEALTH EFFECTS

ACUTE HEALTH EFFECTS

SWALLOWED

  Swallowing of the liquid may cause aspiration into the lungs with the risk of chemical pneumonitis; serious consequences may result. (ICSC13733).  Accidental ingestion of the material may be damaging to the health of the individual.  Overexposure to non-ring alcohols causes nervous system symptoms. These include headache, muscle weakness and inco-ordination, giddiness, confusion, delirium and coma. Digestive symptoms may include nausea, vomiting and diarrhea. Aspiration is much more dangerous than ingestion because lung damage can occur and the substance is absorbed into the body. Alcohols with ring structures and secondary and tertiary alcohols cause more severe symptoms, as do heavier alcohols.  Ingestion of propylene glycol produced reversible central nervous system depression in humans following ingestion of 60 ml. Symptoms included increased heart-rate (tachycardia),  excessive sweating (diaphoresis) and grand mal seizures in a 15 month child who ingested large doses (7.5 ml/day for 8 days) as an ingredient of vitamin preparation.  Excessive repeated ingestions may cause hypoglycaemia (low levels of glucose in the blood stream) among susceptible individuals; this may result in muscular weakness, incoordination and mental confusion.  Very high doses given during feeding studies to rats and dogs produce central nervous system depression (although one-third of that produced by ethanol), haemolysis and insignificant kidney changes.  In humans propylene glycol is partly excreted unchanged in the urine and partly metabolised as lactic and pyruvic acid. Lactic acidosis may result.  

EYE

  Irritation of the eyes may produce a heavy secretion of tears (lachrymation).  Limited evidence or practical experience suggests, that the material may cause eye irritation in a substantial number of individuals. Prolonged eye contact may cause inflammation characterized by a temporary redness of the conjunctiva (similar to windburn).  

SKIN

  The material may cause moderate inflammation of the skin either following direct contact or after a delay of some time. Repeated exposure can cause contact dermatitis which is characterized by redness, swelling and blistering.  A single prolonged exposure is not likely to result in the material being absorbed in harmful amounts. However the material may be absorbed in potentially harmful amounts when applied in large quantities to severe burns (second or third degree) over large areas of the body as part of a cream, other topical application or by prolonged contact with clothing accidentally wetted by the material. Absorption under such circumstances can elevated serum osmolality and may result in osmotic shock.  Most liquid alcohols appear to act as primary skin irritants in humans. Significant percutaneous absorption occurs in rabbits but not apparently in man.  Open cuts, abraded or irritated skin should not be exposed to this material.  Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may produce systemic injury with harmful effects. Examine the skin prior to the use of the material and ensure that any external damage is suitably protected.  

INHALED

  Inhalation may produce health damage*.  Inhalation of vapours may cause drowsiness and dizziness. This may be accompanied by narcosis, reduced alertness, loss of reflexes, lack of coordination and vertigo.  Inhalation of vapors or aerosols (mists, fumes), generated by the material during the course of normal handling, may be damaging to the health of the individual.  Inhalation hazard is increased at higher temperatures.  Aliphatic alcohols with more than 3-carbons cause headache, dizziness, drowsiness, muscle weakness and delirium, central depression, coma, seizures and behavioral changes. Secondary respiratory depression and failure, as well as low blood pressure and irregular heart rhythms, may follow. Nausea and vomiting are seen, and liver and kidney damage is possible as well following massive exposures. Symptoms are more acute the more carbons there are in the alcohol.  

CHRONIC HEALTH EFFECTS

  There has been some concern that this material can cause cancer or mutations but there is not enough data to make an assessment.  Limited evidence suggests that repeated or long-term occupational exposure may produce cumulative health effects involving organs or biochemical systems.  There is limited evidence that, skin contact with this product is more likely to cause a sensitization reaction in some persons compared to the general population.  There is some evidence that human exposure to the material may result in developmental toxicity. This evidence is based on animal studies where effects have been observed in the absence of marked maternal toxicity, or at around the same dose levels as other toxic effects but which are not secondary non-specific consequences of the other toxic effects.  Secondary amines may react with nitrites to form potentially carcinogenicN-nitrosamines.  Long term exposure to morpholine and some of its congeners may produce liver and kidney damage. Obvious evidence of chronic nasal irritation and inflammation and ocular injury (including retinal degeneration, corneal irritation, uveitis and corneal damage) has been documented in rats exposed to 150 ppm, 6 hours/day, 5 days/week for 104 weeks. Earlier reports linking exposure to morpholine with an increased incidence of hepatocellular carcinoma and pulmonary angiosarcoma, probably resulted from exposure to the carcinogenic contaminant, N-nitrosomorpholine. It must be noted, however, that there is a potential to convert morpholine, a secondary amine), in the body, to the potentially carcinogenic N-  nitros-morpholine. N-nitroso-compounds represent a major class of important chemical carcinogens and mutagens. The induction of tumours by single doses of these substances testify to their potency. Whilst it is difficult to extrapolate animal carcinogenicity data to humans, such data strongly suggests that these compounds are human carcinogens. As a rule the N-nitrosamines as a group are carcinogenic in a multitude of organs and tissues. This is also true for the individual N-nitrosamines where the tumour localisation does not depend only on the kind of nitrosamine but also the species and dose. Mostly, however, a preferred target organ (or even several) can be identified. This is frequently the liver.