QUATERNIUM 26
Flammability | 1 | |
Toxicity | 2 | |
Body Contact | 2 | |
Reactivity | 0 | |
Chronic | 0 | |
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4 |
Quaternary ammonium compound.
"1-propanaminium, 3-amino-N-(2-hydroxyethyl)-N, N-dimethyl-, N-(mink oil)acyl
derivatives, chlorides", "1-propanaminium, 3-amino-N-(2-hydroxyethyl)-N, N-dimethyl-,
N-(mink oil)acyl derivatives, chlorides", "(3-minkamidopropyl)dimethyl(2-
hydroxyethyl)ammonium chloride", "quaternary ammonium compounds,
(hydroxyethyl)dimethyl(3-mink oilamidopropyl), chlorides", "minkamidopropyl dimethyl 2-
hydroxyethyl ammonium chloride", "minkamidopropyl dimethyl 2-hydroxyethyl ammonium
chloride"
None
Toxic to aquatic organisms.
Although ingestion is not thought to produce harmful effects, the material may still be damaging to the health of the individual following ingestion, especially where pre- existing organ (e.g. liver, kidney) damage is evident. Present definitions of harmful or toxic substances are generally based on doses producing mortality (death) rather than those producing morbidity (disease, ill-health). Gastrointestinal tract discomfort may produce nausea and vomiting. In an occupational setting however, ingestion of insignificant quantities is not thought to be cause for concern. Considered an unlikely route of entry in commercial/industrial environments. Concentrated solutions of many cationics may cause corrosive damage to mucous membranes and the esophagus. Nausea and vomiting (sometimes bloody) may follow ingestion. Serious exposures may produce an immediate burning sensation of the mouth, throat and abdomen with profuse salivation, ulceration of mucous membranes, signs of circulatory shock (hypotension, labored breathing, and cyanosis) and a feeling of apprehension, restlessness, confusion and weakness. Weak convulsive movements may precede central nervous system depression. Erosion, ulceration, and petechial hemorrhage may occur through the small intestine with glottic, brain and pulmonary edema. Death may result from asphyxiation due to paralysis of the muscles of respiration or cardiovascular collapse. Fatal poisoning may arise even when the only pathological signs are visceral congestion, swallowing, mild pulmonary edema or varying signs of gastrointestinal irritation. Individuals who survive a period of severe hypertension may develop kidney failure. Cloudy swelling, patchy necrosis and fatty infiltration in such visceral organs as the heart, liver and kidneys shows at death.
There is some evidence to suggest that this material can causeeye irritation and damage in some persons. Many cationic surfactants are very irritating to the eyes at low concentration. Concentrated solutions can cause severe burns with permanent clouding.
The material is not thought to produce adverse health effects or skin irritation following contact (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable gloves be used in an occupational setting. Cationic surfactants cause skin irritation, and, in highconcentrations, caustic burns.
The material is not thought to produce adverse health effects or irritation of the respiratory tract (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable control measures be used in an occupational setting. Persons with impaired respiratory function, airway diseases and conditions such as emphysema or chronic bronchitis, may incur further disability if excessive concentrations of particulate are inhaled.
Principal routes of exposure are usually by skin contact/absorption and inhalation of generated dust. No human exposure data available. For this reason health effects described are based on experience with chemically related materials. As with any chemical product, contact with unprotected bare skin; inhalation of vapor, mist or dust in work place atmosphere; or ingestion in any form, should be avoided by observing good occupational work practice.