LEAD NITRATE
Flammability | 0 | |
Toxicity | 3 | |
Body Contact | 2 | |
Reactivity | 2 | |
Chronic | 3 | |
SCALE: Min/Nil=0 Low=1 Moderate=2 High=3 Extreme=4 |
Used as a reagent in analytical chemistry; in the manufacture of matches and special
explosives; as a mordant in dyeing and printing of textiles; as a sensitiser in
photography.
Pb(NO3)2, N2-O6-Pb, "lead dinitrate", "lead(2+) nitrate", "nitric acid, lead(2+) salt"
Contact with combustible material may cause fire.
Danger of cumulative effects.
Irritating to eyes.
May cause harm to the unborn child.
Possible risk of impaired fertility.
Harmful: danger of serious damage to health by prolonged exposure through
inhalation, in contact with skin and if swallowed.
Harmful by inhalation and if swallowed.
Very toxic to aquatic organisms, may cause long- term adverse effects in the
aquatic environment.
Accidental ingestion of the material may be harmful; animal experiments indicate that ingestion of less than 150 gram may be fatal or may produce serious damage to the health of the individual. The substance and/or its metabolites may bind to hemoglobin inhibiting normal uptake of oxygen. This condition, known as "methemoglobinemia", is a form of oxygen starvation (anoxia). Symptoms include cyanosis (a bluish discoloration skin and mucous membranes) and breathing difficulties. Symptoms may not be evident until several hours after exposure. At about 15% concentration of blood methemoglobin there is observable cyanosis of the lips, nose and earlobes. Symptoms may be absent although euphoria, flushed face and headache are commonly experienced. At 25-40%, cyanosis is marked but little disability occurs other than that produced on physical exertion. At 40-60%, symptoms include weakness, dizziness, lightheadedness, increasingly severe headache, ataxia, rapid shallow respiration, drowsiness, nausea, vomiting, confusion, lethargy and stupor. Above 60% symptoms include dyspnea, respiratory depression, tachycardia or bradycardia, and convulsions. Levels exceeding 70% may be fatal.
This material can cause eye irritation and damage in some persons.
The material is not thought to produce adverse health effects or skin irritation following contact (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable gloves be used in an occupational setting.
There is some evidence to suggest that this material, if inhaled, can irritate the throat and lungs of some persons. Persons with impaired respiratory function, airway diseases and conditions such as emphysema or chronic bronchitis, may incur further disability if excessive concentrations of particulate are inhaled.
Ample evidence exists that developmental disorders are directlycaused by human exposure to the material.
Principal routes of exposure are by accidental skin and eye contact andinhalation of generated dusts. Lead, in large amounts, can affect the blood, nervous system, heart, glands, immune system and digestive system. Anemia may occur. If untreated muscles may become paralyzed, and there may be brain damage. Symptoms include joint and muscle pain, weakness in the back of the forearm and wrist and in the shin muscles, headaches, dizziness, abdominal pain, diarrhea or constipation, nausea, vomiting, blue line on gums, sleep disturbance and a metallic taste in the mouth. The pressure in the brain may increase with high doses, and cause brain damage, coma, and death. Early signs include loss of appetite and weight, constipation, tiredness and irritability, headache, weakness. Later there may be vomiting, nervousness, and muscle pains in the arms and legs. Serious cases cause severe vomiting, inco-ordination, stupor, permanent eye damage, high blood pressure, multiple nerve disorders of the head resulting in paralysis and loss of reflexes, delirium, convulsions and coma. The kidneys may become irreversibly damaged, and the nervous system may become affected causing mental retardation, cerebral palsy, and jerks and seizures. Lead can cross the placenta, and cause miscarriage, stillbirths and birth defects. Exposure before birth can cause mental retardation, behavioral disorders and infant death. Lead can also cause reduced sex drive, impotence, sterility and damage the sperm of males, increasing the potential for birth defects. Periods in women can also be affected. Lead can accumulate in the skeleton for a very long time.