Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

PRODUCT NAME

JASMONIC ACID

STATEMENT OF HAZARDOUS NATURE

Not considered a hazardous substance according to OSHA 29 CFR 1910.1200.

NFPA

PRODUCT USE

(- ) ?jasmonic acid and it methyl esters are ubiquitous in plants. They have hormone
properties, help regulating plant growth and development and they seem to participate in
leaf senescence and in the defence mechanism against fungi. Just like all other plant
hormones have jasmonates both activating and inhibiting effects. Synergistic and
antagonistic effects on other hormones have been observed, too. Jasmonate derivatives
induce the accumulation of so- called jasmonate- induced- proteins that were found in all
plant species tested. Their accumulation can also be caused by desiccation or ABA effects.
Jasmonate- induced- proteins are of varying molecular weights, and molecules of different
size classes have immunologically been shown to be related. The major portion of these
proteins is not glycosylated, has no proteolytic activity and is metabolically stable.
Labelling with immunogold and electron microscopy showed that some of them are located
within the nucleus, while others were detected in the vacuole. None have ever been found
in mitochondria. Their synthesis can be inhibited by cycloheximid, but not by
chloramphenicol. Chloramphenicol affects mitochondrial proteins. Jasmonate- induced-
proteins are lacking in roots, in bleached leaves, and in leaves of chlorophyll- deficient
Hordeum vulgare mutants. They exist in etiolated leaves, though. Jasmonates do not only
regulate the transcription of these proteins, they do also influence the rate of
translation of different groups of mRNA. They do, for example, decrease the production
rate of several essential housekeeping proteins. Just like ABA inhibit jasmonates a
premature germination of the oil- containing seeds of Brassica and Linum. After
germination do they induce the synthesis of the seed storage proteins Napin and Cruciferin
as well as that of several more elaiosome- associated proteins (PARTHIER, 1991).
(PARTHIER, 1991). (- ) ?jasmonic acid and it methyl esters are ubiquitous in plants. They
have hormone properties, help regulating plant growth and development and they seem to
participate in leaf senescence and in the defence mechanism against fungi. Just like all
other plant hormones have jasmonates both activating and inhibiting effects. Synergistic
and antagonistic effects on other hormones have been observed, too. Jasmonate derivatives
induce the accumulation of so- called jasmonate- induced- proteins that were found in all
plant species tested. Their accumulation can also be caused by desiccation or ABA effects.
Jasmonate- induced- proteins are of varying molecular weights, and molecules of different
size classes have immunologically been shown to be related. The major portion of these
proteins is not glycosylated, has no proteolytic activity and is metabolically stable.
Labelling with immunogold and electron microscopy showed that some of them are located
within the nucleus, while others were detected in the vacuole. None have ever been found
in mitochondria. Their synthesis can be inhibited by cycloheximid, but not by
chloramphenicol. Chloramphenicol affects mitochondrial proteins. Jasmonate- induced-
proteins are lacking in roots, in bleached leaves, and in leaves of chlorophyll- deficient
Hordeum vulgare mutants. They exist in etiolated leaves, though. Jasmonates do not only
regulate the transcription of these proteins, they do also influence the rate of
translation of different groups of mRNA. They do, for example, decrease the production
rate of several essential housekeeping proteins. Just like ABA inhibit jasmonates a
premature germination of the oil- containing seeds of Brassica and Linum. After
germination do they induce the synthesis of the seed storage proteins Napin and Cruciferin
as well as that of several more elaiosome- associated proteins (PARTHIER, 1991).
(PARTHIER, 1991).

SYNONYMS

C12-H18-O3, "2[(1R, 2R)-2-((2Z)pent-2-enyl)-3-oxocyclopentyl]acetic acid", "2[(1R, 2R)-2-
((2Z)pent-2-enyl)-3-oxocyclopentyl]acetic acid", "(1R, 2R)-3-oxo-2-(Z)-pent-2-
enylcyclopentylacetic acid", "(1R, 2R)-3-oxo-2-(Z)-pent-2-enylcyclopentylacetic acid",
"(1R, 2R)-3-oxo-2-(2Z)-2-pentenylcyclopentaneacetic acid", "(1R, 2R)-3-oxo-2-(2Z)-2-
pentenylcyclopentaneacetic acid", "1alpha, 2beta-3-oxo-2-(cis-2-
pentenyl)cyclopentaneacetic acid", "1alpha, 2beta-3-oxo-2-(cis-2-
pentenyl)cyclopentaneacetic acid", "(-)-jasomonic acid - CAS RN", 6894-38-8], 6894-38-8],
"plant hormone", "plant growth reglator/ growth inhibitor"

Section 2 - HAZARDS IDENTIFICATION

CANADIAN WHMIS SYMBOLS

None

EMERGENCY OVERVIEW

RISK

POTENTIAL HEALTH EFFECTS

ACUTE HEALTH EFFECTS

SWALLOWED

  The material has NOT been classified as "harmful by ingestion". This is because of the lack of corroborating animal or human evidence. The material may still be damaging to the health of the individual, following ingestion, especially where pre-existing organ (e.g. liver, kidney) damage is evident. Present definitions of harmful or toxic substances are generally based on doses producing mortality (death) rather than those producing morbidity (disease, ill-health). Gastrointestinal tract discomfort may produce nausea and vomiting. In an occupational setting however, unintentional ingestion is not thought to be cause for concern.  

EYE

  Although the liquid is not thought to be an irritant, direct contact with the eye may produce transient discomfort characterized by tearing or conjunctival redness (as with windburn).  

SKIN

  The material is not thought to produce adverse health effects or skin irritation following contact (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable gloves be used in an occupational setting.  

INHALED

  The material is not thought to produce adverse health effects or irritation of the respiratory tract (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable control measures be used in an occupational setting.  

CHRONIC HEALTH EFFECTS

  Long-term exposure to the product is not thought to produce chronic effects adverse to the health (as classified using animal models); nevertheless exposure by all routes should be minimized as a matter of course.