Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION

PRODUCT NAME

LANTHANUM(III) DIBUTYLPHOSPHATE

NFPA

PRODUCT USE

Reagent.

SYNONYMS

C8-H19-O4-P.1/3La, "phosphoric acid, dibutyl ester, lanthanum(3+) salt", "butyl
lanthanum phosphate (La[O2P(OBu)2]3)", "lanthanum butyl phosphate (La[O2P(OBu)2]3)",
"lanthanum dibutylphosphate", "lanthanum(3+) dibutyl phosphate"

Section 2 - HAZARDS IDENTIFICATION

CANADIAN WHMIS SYMBOLS

EMERGENCY OVERVIEW

RISK

POTENTIAL HEALTH EFFECTS

ACUTE HEALTH EFFECTS

SWALLOWED

  The material has NOT been classified as "harmful by ingestion". This is because of the lack of corroborating animal or human evidence. The material may still be damaging to the health of the individual, following ingestion, especially where pre-existing organ (e.g. liver, kidney) damage is evident. Present definitions of harmful or toxic substances are generally based on doses producing mortality (death) rather than those producing morbidity (disease, ill-health). Gastrointestinal tract discomfort may produce nausea and vomiting. In an occupational setting however, unintentional ingestion is not thought to be cause for concern.  

EYE

  Although the material is not thought to be an irritant, direct contact with the eye may cause transient discomfort characterized by tearing or conjunctival redness (as with windburn). Slight abrasive damage may also result. The material may produce foreign body irritation in certain individuals.  

SKIN

  The material is not thought to produce adverse health effects or skin irritation following contact (as classified using animal models). Nevertheless, good hygiene practice requires that exposure be kept to a minimum and that suitable gloves be used in an occupational setting.  Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may produce systemic injury with harmful effects. Examine the skin prior to the use of the material and ensure that any external damage is suitably protected.  

INHALED

  Inhalation of dusts, generated by the material during the course of normal handling, may be damaging to the health of the individual.  There is some evidence to suggest that the material can cause respiratory irritation in some persons. The body's response to such irritation can cause further lung damage.  Persons with impaired respiratory function, airway diseases and conditions such as emphysema or chronic bronchitis, may incur further disability if excessive concentrations of particulate are inhaled.  Exposure to vapors of some rare earth salts can cause sensitivity to heat, itching, and increased sensitivity of smell and taste. Other effects include inflamed airways and lung,  emphysema, regional narrowing of terminal airways and cell changes. Rarely, excess blood flow has occurred following a delay. Lung cancers can also occur.  Organic phosphates are very stable and highly hazardous. There are a number of effects they can have on the body, including excitement of the central nervous system, and irritation of the skin and respiratory tract. Alkyl phosphates do not cause nerve damage, but they do excite the nervous system and irritate the respiratory tract, eye and skin, and can be absorbed through the skin.  

CHRONIC HEALTH EFFECTS

  Limited evidence suggests that repeated or long-term occupational exposure may produce cumulative health effects involving organs or biochemical systems.  Long term exposure to high dust concentrations may cause changes in lung function i.e. pneumoconiosis; caused by particles less than 0.5 micron penetrating and remaining in the lung. Prime symptom is breathlessness; lung shadows show on X-ray.  Lanthanum is one of the rare earth metals - light type (cerium family). Rare earth metals have not been shown to have toxic effects, but dust inhalation can still cause scarring of the lungs.